The Global Challenge

The Global Challenge is an ACRES-developed collaborative model for funding and implementing capacity building activities in countries without a well-established clinical research capacity. Today, a sponsor company interested in placing trials in such nations faces daunting challenges and great expense, with considerable risk, owing to the uncertainty about ethical, regulatory, safety and quality parameters resulting from the lack of well-established standards and potentially unreliable capacity for study performance.

The Global Challenge addresses these uncertainties by identifying countries willing to make strong commitments to development of sustainable world-class research systems to which industry investment can be directed and amplified in partnership with non-profit organizations interested in supporting such development and its attendant social, academic and economic benefits. These benefits directly improve both economic vitality and health in the host countries and enhance capacity for health-related research.

The Challenge is grounded in a pilot model, a novel public-private partnership, potentially built around a specific research project to address a serious disease burden that can also be extrapolated for a range of research programs and projects. Resources that would traditionally be expended on a single trial become a lasting investment in the host country’s clinical trial system and infrastructure.

Progress and success measures are monitored throughout the project. Ultimately, a successful outcome will be marked by timely and successful completion of the Sponsor’s trial and the creation of a sustainable clinical trial capability

Several countries have expressed interest in the ACRES approach, including Bangladesh, India, Sri Lanka, Malaysia, Indonesia, China, Pakistan, Bulgaria, the Czech Republic, Russia, Saudi Arabia, Turkey, Vietnam, Colombia, and several countries in Africa.